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    Waistlines in People, Glucose Levels in Mice Hint at Sweeteners’ Effects: Related Studies Point to the Illusion of the Artificial
    ScienceDaily (June 27, 2011) — In the constant battle to lose inches or at least stay the same, we reach for the diet soda. Two studies presented June 25 and 27 at the American Diabetes Association’s Scientific Sessions in San Diego suggest this might be self-defeating behavior.—epidemiologists from the School of Medicine at The University of Texas Health Science Center San Antonio reported data showing that diet soft drink consumption is associated with increased waist circumference in humans, and a second study that found aspartame raised fasting glucose (blood sugar) in diabetes-prone mice.–“Data from this and other prospective studies suggest that the promotion of diet sodas and artificial sweeteners as healthy alternatives may be ill-advised,” said Helen P. Hazuda, Ph.D., professor and chief of the Division of Clinical Epidemiology in the School of Medicine. “They may be free of calories but not of consequences.” Human study-The San Antonio Longitudinal Study of Aging—To examine the relationship between diet soft drink consumption and long-term change in waist circumference, the Health Science Center team assessed data from 474 participants in the San Antonio Longitudinal Study of Aging, or SALSA. This is a large, population-based study of the disablement process in elderly Mexican Americans and European Americans. Dr. Hazuda, senior author of the presentation, is SALSA’s principal investigator and has led the study for two decades.—Measures of height, weight, waist circumference and diet soda intake were recorded at SALSA enrollment and at three follow-up exams that took place over the next decade. The average follow-up time was 9.5 years. The researchers compared long-term change in waist circumference for diet soda users versus non-users in all follow-up periods. The results were adjusted for waist circumference, diabetes status, leisure-time physical activity level, neighborhood of residence, age and smoking status at the beginning of each interval, as well as sex, ethnicity and years of education.—Diet soft drink users, as a group, experienced 70 percent greater increases in waist circumference compared with non-users. Frequent users, who said they consumed two or more diet sodas a day, experienced waist circumference increases that were 500 percent greater than those of non-users.—Abdominal fat is a major risk factor for diabetes, cardiovascular disease, cancer and other chronic conditions. “These results suggest that, amidst the national drive to reduce consumption of sugar-sweetened drinks, policies that would promote the consumption of diet soft drinks may have unintended deleterious effects,” the authors wrote.Co-authors include Sharon P. Fowler, M.P.H., faculty associate, and Ken Williams, M.S., P.Stat., adjunct assistant professor and biostatistician, in the Division of Clinical Epidemiology.
    Mouse study- Aspartame consumption in diabetes-prone mice
    In the related project, Ganesh Halade, Ph.D., Gabriel Fernandes, Ph.D., the senior author and professor of rheumatology and clinical immunology, and Fowler studied the relationship between oral exposure to aspartame and fasting glucose and insulin levels in 40 diabetes-prone mice. Aspartame is an artificial sweetener widely used in diet sodas and other products.-One group of the mice ate chow to which both aspartame and corn oil were added; the other group ate chow with the corn oil added but not the aspartame. After three months on this high-fat diet, the mice in the aspartame group showed elevated fasting glucose levels but equal or diminished insulin levels, consistent with early declines in pancreatic beta-cell function. The difference in insulin levels between the groups was not statistically significant. Beta cells make insulin, the hormone that lowers blood sugar after a meal. Imbalance ultimately leads to diabetes.—“These results suggest that heavy aspartame exposure might potentially directly contribute to increased blood glucose levels, and thus contribute to the associations observed between diet soda consumption and the risk of diabetes in humans,” Dr. Fernandes said.—These two translational research studies resulted from collaboration between Fowler and Drs. Hazuda and Fernandes and their research teams. The Institute for the Integration of Medicine and Science (IIMS) funded the work. IIMS is the Health Science Center entity that oversees the university’s Clinical and Translational Science Award (CTSA), a National Institutes of Health-funded program to encourage the rapid translation of scientific discoveries from the laboratory through the testing process and to practical application for the health of communities.-Story Source-The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Texas Health Science Center at San Antonio.
    Alternate-Day Fasting: How Good Is It For Your Health?
    ScienceDaily (Sep. 22, 2007) — Researchers report that fasting or eating half as much as usual every other day may shrink your fat cells and boost mechanisms that break down fats. —Consuming less calories and increasing physical activity is usually what people do to lose weight and stay healthy. But some people prefer to adopt a diet which consists of eating as much as they want one day while fasting the next. On each fasting day, these people consume energy-free beverages, tea, coffee, and sugar-free gum and they drink as much water as they need. —Although many people claim that this diet, called alternate-day fasting (ADF), help them lose weight and improved their health, the effects on health and disease risk of ADF are not clear. –Krista Varady and colleagues studied the effects of alternate-day fasting on 24 male mice for four weeks. To assess the impact of ADF on the health of the mice, the scientists not only tested mice that followed and didn’t follow an ADF diet, but they also studied mice that followed the diet only partially: a group of mice consumed 50 percent of their regular diet every other day (ADF-50%) and another consumed 75 percent of their regular diet every other day (ADF-25%). -The scientists noticed that the ADF-100% mice lost weight and the fat cells of both the ADF-100% and ADF-50% groups shrunk by more than half and by 35 percent, respectively. Also, in these two groups of mice, fat under the skin — but not abdominal fat — was broken down more than in mice that did not follow the diet. —These results suggest that complete and modified ADF regimens seem to protect against obesity and type 2 diabetes but do not result in fat or weight loss. More studies will be needed to confirm whether the long-term effects of ADF regimens are beneficial for health and reduce disease risk, the scientists conclude.–Article: “Effects of modified alternate-day fasting regimens on adipocyte size, triglyceride metabolism and plasma adiponectin levels in mice,” by Krista A. Varady, D. J. Roohk, Y. C. Loe, B. K. McEvoy-Hein, and M. K. Hellerstein–Story Source– The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by American Society for Biochemistry and Molecular Biology, via EurekAlert!, a service of AAAS.
    Surprising Drop in Physicians’ Willingness to Accept Patients With Insurance, U.S. Study Finds
    ScienceDaily (June 27, 2011) — As required under the U.S. Patient Protection and Affordable Care Act of 2010, millions of people will soon be added to the ranks of the insured. However, this rapid expansion of coverage is colliding with a different, potentially problematic trend that could end up hampering access to health care.–Since 2005, doctors have been accepting fewer and fewer patients with health insurance, according to a new study published in the June 27th issue of Archives of Internal Medicine. As a result, says Dr. Tara Bishop, assistant professor of public health at Weill Cornell Medical College, and lead author of the study, insured patients could face new obstacles to receiving the medical attention they need, and overall access to health care could actually contract.–Dr. Bishop, who is also a practicing physician at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, and her fellow investigators looked at survey data from a national survey run by the CDC’s National Center for Health Statistics and found an overall decline in physician acceptance of several types of insurance. First, they noted a modest drop in acceptance of Medicare patients, from 95.5 percent in 2005 to 92.9 percent in 2008. Doctors also turned more and more Medicaid patients away over the four-year period — a phenomenon the authors attribute to Medicaid’s historically low reimbursement rates. But the most surprising decline of all was seen in doctors’ acceptance of new patients with private insurance.–“Given the medical profession’s widely reported dissatisfaction with Medicare, we expected to find hard evidence that Medicare patients were being turned away,” Dr. Bishop says. “Instead, we saw only a modest decline in doctors’ acceptance of patients on Medicare. The survey data showed a more significant decline in their acceptance of patients with private insurance.”–Physician acceptance of patients with traditional fee-for-service private insurance declined from 93.3 percent in 2005 to 87.8 percent in 2008.–This change could be traceable to two major factors, she explains: inadequate reimbursement levels that have not kept pace with medical practice expenditures; and the tangle of administrative issues that go hand in hand with private health insurance.—“At a moment when the country is poised to achieve near-universal coverage, patients’ access to care could be a casualty of the collision between the medical profession and the insurance industry,” says Dr. Bishop.–The study was co-authored by Drs. Alex Federman of the Mount Sinai School of Medicine and Salomeh Keyhani of the University of California, San Francisco. The researchers hope their study will alert policymakers to potential problems in health care access, exacerbated by current shortages in primary care, an aging population, the growing prevalence of serious chronic diseases, and the imminent expansion of health insurance coverage as mandated under health care reform. “Consumers and health advocacy groups, too, should be aware of these early warning signs so that they can work to ensure access to quality medical care,” adds Dr. Bishop. Story Source-The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by Weill Cornell Medical College.-
    Journal Reference-Tara F. Bishop; Alex D. Federman; Salomeh Keyhani. Declines in Physician Acceptance of Medicare and Private Coverage. Archives of Internal Medicine, 2011; 171 (12): 1117-1119 DOI: 10.1001/archinternmed.2011.251
    The Myth of low Fat –High Carb Diet
    By Joel M. Kauffman, PhD
    Digestible carbohydrate (carb) is usually sugar or starch. The name came from the simplest formula that showed only which atoms in a carb were present and their ratio: CH2O. This looked like a hydrate (H2O) of carbon (C), thus carbohydrate. —Non-insulin-dependent diabetes mellitus (NIDDM) is a result of excessive carbohydrate consumption, which leads to excessive insulin production in people who are carb-sensitive genetically. NIDDM is also called adult-onset or Type-II or Type-2 diabetes.–
    Milder cases are called insulin resistance or Syndrome X. Insulin-dependent diabetes mellitus (IDDM), also called juvenile onset or Type-I or Type-1 diabetes, is a result of destruction of most of the insulin-producing beta cells of the pancreas, and injected insulin is an essential component of successful treatment.—Even so, eating much less carb than the American norm (45% food energy from carb) allows low blood sugar (serum glucose) to be maintained, and prevents many of the side-effects of high serum glucose (atherosclerosis for one), and low sugar (fainting from hypoglycemia for one), at least in the very carb-sensitive quarter of us. There is also a lesser benefit in the slightly carb-sensitive half of us.—In an ancient tale from Herodotus from the 5th century BC, Persians who already ate wheat bread did not commonly live beyond 80 years, even though they drank red wine. They were in contact with Ethiopians who ate boiled meat and drank milk, and claimed to live commonly to 120!–By 1825, the Frenchman A. B. Savarin had published on the connection between eating flour (starch) and obesity. In 1862 the coffin maker William Banting, who was so fat at age 64 that he could only go down stairs backward, had a serious umbilical hernia, weakness, and was going deaf. —His unusual physician recommended that Banting give up bread, sugar, beer and potatoes, his main foods. Banting lost 46 pounds the first year. The other problems went away, and Banting remained on the diet until his death at age 81, unusual then for English males.–Vilhjalmur Stefansson, MD, beginning at age 27 in 1906, spent a total of 15 years with the Canadian Eskimos, including eating their obviously healthful high-fat no-carb diet, which he grew to prefer. There are reports of many Eskimos living into their 90s in the 18th century. —In 1928 Stefansson and a former companion, Karsten Anderson, MD, entered Bellevue Hospital in New York for a 1-year trial of Eskimo diets. Anderson did well with an all-meat diet, but Stefansson required considerable fat to feel his best, finally settling on 80% fat and 20% protein, with a total caloric intake of 2000-3100 kcal/day. —His total cholesterol went down about 10 mg/dL[U1]. All kinds of other tests were done, but no bad effects of his diet were seen. In the last 6 years of his life, Stefansson returned to his Arctic diet until his death at age 83, spending a total of 22 years on such a diet.
    Richard K. Bernstein, was diagnosed with IDDM at the age of 12 in 1946. Following the advice of the American Heart Association (AHA) and the American Diabetes Association (ADbA) to eat a high-carb (40%, then 60% carb) diet, his condition worsened and most of the complications of IDDM began to appear. He found that he could not normalize his blood sugars with any insulin regimen, and that exercise in his condition did not help. By doing a literature search himself in 1965, he realized the potential benefits of normal blood sugars.—By using himself as the test animal he found that about 30 g/day of slow-acting carbohydrate (essentially fiber with no simple sugars or high GI starches at all) was necessary to normalize his blood glucose levels, the rest of his diet being fat and protein. He obtained an MD degree at about age 45 partly to have his observations published in medical journals, because the papers were rejected when he did not have the MD degree. —He has continued the diet for 35 years so far, which includes on many days, 3 eggs for breakfast and no fruit. His total cholesterol dropped from 300 mg/dL to 179, of which LDL-C = 63 and HDL-C = 116 (that is not a misprint). His triglycerides dropped from 250 to 45. His lipoprotein(a) level, a marker of inflammation, became undetectable. In 1983 he began his own medical practice for diabetics. At the time of writing he is age 72 and he still works 12-14 hour days in his medical practice on diabetics—In 1956 Prof. Alan Kekwick and Gaston Pawan, MD, at Middlesex Hospital, London, England, conducted tests of 4 varieties of 1,000 kcal/day diets: 90% fat (by fuel values), 90% protein, 90% carbohydrate, and a normal mixed diet. — Subjects on the high-fat diet lost much more weight than any of the others. Several subjects on the high-carb diet actually gained weight, even at only 1000 kcal/day! Even at 2,600 kcal/day of very low-carb diet, subjects lost weight. Thus the dogma that a “balanced” diet is best for almost everyone had been falsified a half century ago.—All honestly-run low-carb diet trials show benefits, even ones where the researchers expected the opposite. Examination of at least two dozen recent controlled diet trials by an equal number of authors in several countries led them to these conclusions:
    1. Carb restriction improved control of serum glucose, the primary target of nutritional therapy, and reduced insulin fluctuations.
    2. Carb-restricted diets are at least as effective for weight loss as low-fat diets.
    3. Substitution of fat for carb is generally beneficial for markers of and for the actual incidence of cardiovascular disease. [This means that a diet of 25% carb, 25% protein and 50% fat will be optimum for many folks. Some have followed such diets for over 50 years.]
    4. Carb restriction has benefits even in the absence of weight loss.
    From: Nutrition & Metabolism 2008;5:9.
    And the reaction of all government agencies and most private foundations? Intransigence! The American Diabetes Association (ADbA) recommends 60% high-GI carbs in the diet without reservation in 2003 (and 50% now): “The message today: Eat more starches! —It is healthiest, they say, for everyone to eat more whole grains, beans, and starchy vegetables such as peas, corn, potatoes and winter squash. Starches are good for you because they have very little fat, saturated fat, or cholesterol… Yes, foods with carbohydrate — starches, vegetables, fruits, and dairy products — will raise your blood glucose more quickly than meats and fats, but they are the healthiest foods for you. –Your doctor may need to adjust your medications when you eat more carbohydrates. You may need to increase your activity level or try spacing carbohydrates throughout the day… the American Diabetes Association nutrition recommendations…are based on years of research and clinical experience. In addition, these trendy diets are hard to follow year after year.” As though Banting, Stefansson, Kekwick, Bernstein, Atkins, Eades & Eades, and millions of others never existed.—With nearly 70,000 members, the American Dietetic Association (ADtA) is the nation’s largest organization of food and nutrition professionals. The ADtA serves the public by promoting optimal nutrition, health and well-being.” The AdtA endorses the Food Guide Pyramid of the United States Department of Agriculture (USDA) unequivocally, thus recommending high-carb diets with 75% carb, 10% fat and 15% protein.[U2]–The US Food and Drug Administration (FDA) recommends high-carb diets with caloric content of 55% carb, 30% fat (1/3 each saturated, monounsaturated, polyunsaturated) and 15% protein.—The American Heart Association (AHA) recommends the use of a food pyramid with about the same caloric content from each of the food groups as in the USDA pyramid. Differences are that the AHA recommends no egg yolks at all, and otherwise to avoid saturated fat and cholesterol intake at all costs; also the positions of some foods are changed. The AHA favors small amounts of soft margarine, [U3]and large amounts of milk and low-fat milk and other dairy products, with no exceptions for diabetics that are apparent on the website.
    On their new web pages for diabetics: “Type 2 diabetes is a progressive disease that develops when the body does not produce enough insulin [sic] and does not efficiently use the insulin it does produce (a phenomenon known as insulin resistance)…” (Italics added.) The AHA notes that the World Health Organization Study (WHO) Group recommends that 15% of total calories be derived from fat, and is concerned that certain key nutrient levels will not be met in certain population groups at this level.—There is no better example in history of bureaucrats ignoring data to protect their reputations with billions of tax dollars and donations. Shortening life and its quality for huge populations, causing the obesity and diabetes epidemic, which lead to atherosclerosis and heart problems indicate that institutional loyalty outweighs truth, conscience and morals. —There is no better example in history where your persistence in digging for diet truth in books and journals can do more for your health than the entire diet cabal with its control of the mainstream media and most medical providers.— Mostly excerpted from the book: Malignant Medical Myths, 2006.—Joel M. Kauffman, Ph.D.
    Former Professor of Chemistry of the University of the Sciences in Philadelphia, now Emeritus.-Author of Malignant Medical Myths: Why Medical Treatment Causes 200,000 Deaths per Year June
    [U2]These Bastards are trying to kill off people by breaking down there internal organs and causing an overload and overgrowth of bacteria-fungi-cancer and a complete immune system breakdown–
    [U3]PLASTIC—HEY you can eat Plastic and get Cancer—and that is ok—Eating Butter which is fat will strengthen the heart
    TOP A
    Show of the Week July 4 2011
    Mystery Ingredient in Coffee Boosts Protection Against Alzheimer’s Disease
    BHT –The Healing effects—More info
    How Cavity-Causing Microbes Invade Heart—Special Note
    Turning Vicks into Mutli Remedy
    Mystery Ingredient in Coffee Boosts Protection Against Alzheimer’s Disease
    A yet unidentified component of coffee interacts with the beverage’s caffeine, which could be a surprising reason why daily coffee intake protects against Alzheimer’s disease. –ScienceDaily (June 28, 2011) — A yet unidentified component of coffee interacts with the beverage’s caffeine, which could be a surprising reason why daily coffee intake protects against Alzheimer’s disease. A new Alzheimer’s mouse study by researchers at the University of South Florida found that this interaction boosts blood levels of a critical growth factor that seems to fight off the Alzheimer’s disease process.—The findings appear in the early online version of an article to be published June 28 in the Journal of Alzheimer’s Disease. Using mice bred to develop symptoms mimicking Alzheimer’s disease, the USF team presents the first evidence that caffeinated coffee offers protection against the memory-robbing disease that is not possible with other caffeine-containing drinks or decaffeinated coffee.–Previous observational studies in humans reported that daily coffee/caffeine intake during mid-life and in older age decreases the risk of Alzheimer’s disease. The USF researchers’ earlier studies in Alzheimer’s mice indicated that caffeine was likely the ingredient in coffee that provides this protection because it decreases brain production of the abnormal protein beta-amyloid, which is thought to cause the disease.-The new study does not diminish the importance of caffeine to protect against Alzheimer’s. Rather it shows that caffeinated coffee induces an increase in blood levels of a growth factor called GCSF (granulocyte colony stimulating factor). GCSF is a substance greatly decreased in patients with Alzheimer’s disease and demonstrated to improve memory in Alzheimer’s mice. A just-completed clinical trial at the USF Health Byrd Alzheimer’s Institute is investigating GCSF treatment to prevent full-blown Alzheimer’s in patients with mild cognitive impairment, a condition preceding the disease. The results of that trial are currently being evaluated and should be known soon.–“Caffeinated coffee provides a natural increase in blood GCSF levels,” said USF neuroscientist Dr. Chuanhai Cao, lead author of the study. “The exact way that this occurs is not understood. There is a synergistic interaction between caffeine and some mystery component of coffee that provides this beneficial increase in blood GCSF levels.”—The researchers would like to identify this yet unknown component so that coffee and other beverages could be enriched with it to provide long-term protection against Alzheimer’s.—In their study, the researchers compared the effects of caffeinated and decaffeinated coffee to those of caffeine alone. In both Alzheimer’s mice and normal mice, treatment with caffeinated coffee greatly increased blood levels of GCSF; neither caffeine alone or decaffeinated coffee provided this effect. The researchers caution that, since they used only “drip” coffee in their studies, they do not know whether “instant” caffeinated coffee would provide the same GCSF response.–The boost in GCSF levels is important, because the researchers also reported that long-term treatment with coffee (but not decaffeinated coffee) enhances memory in Alzheimer’s mice. Higher blood GCSF levels due to coffee intake were associated with better memory. The researchers identified three ways that GCSF seems to improve memory performance in the Alzheimer’s mice. First, GCSF recruits stem cells from bone marrow to enter the brain and remove the harmful beta-amyloid protein that initiates the disease. GCSF also creates new connections between brain cells and increases the birth of new neurons in the brain.—“All three mechanisms could complement caffeine’s ability to suppress beta amyloid production in the brain” Dr. Cao said, “Together these actions appear to give coffee an amazing potential to protect against Alzheimer’s — but only if you drink moderate amounts of caffeinated coffee.”—Although the present study was performed in Alzheimer’s mice, the researchers indicated that they’ve gathered clinical evidence of caffeine/coffee’s ability to protect humans against Alzheimer’s and will soon publish those findings.–Coffee is safe for most Americans to consume in the moderate amounts (4 to 5 cups a day) that appear necessary to protect against Alzheimer’s disease. The USF researchers previously reported this level of coffee/caffeine intake was needed to counteract the brain pathology and memory impairment in Alzheimer’s mice. The average American drinks 1½ to 2 cups of coffee a day, considerably less than the amount the researchers believe protects against Alzheimer’s.—“No synthetic drugs have yet been developed to treat the underlying Alzheimer’s disease process” said Dr. Gary Arendash, the study’s other lead author. “We see no reason why an inherently natural product such as coffee cannot be more beneficial and safer than medications, especially to protect against a disease that takes decades to become apparent after it starts in the brain.”—The researchers believe that moderate daily coffee intake starting at least by middle age (30s — 50s) is optimal for providing protection against Alzheimer’s disease, although starting even in older age appears protective from their studies. “We are not saying that daily moderate coffee consumption will completely protect people from getting Alzheimer’s disease,” Dr. Cao said. “However, we do believe that moderate coffee consumption can appreciably reduce your risk of this dreaded disease or delay its onset.”—The researchers conclude that coffee is the best source of caffeine to counteract the cognitive decline of Alzheimer’s because its yet unidentified component synergizes with caffeine to increase blood GCSF levels. Other sources of caffeine, such as carbonated drinks, energy drinks, and tea, would not provide the same level of protection against Alzheimer’s as coffee, they said.–Coffee also contains many ingredients other than caffeine that potentially offer cognitive benefits against Alzheimer’s disease. “The average American gets most of their daily antioxidants intake through coffee,” Dr. Cao said. “Coffee is high in anti-inflammatory compounds that also may provide protective benefits against Alzheimer’s disease.”—An increasing body of scientific literature indicates that moderate consumption of coffee decreases the risk of several diseases of aging, including Parkinson’s disease, Type II diabetes and stroke. Just within the last few months, new studies have reported that drinking coffee in moderation may also significantly reduce the risk of breast and prostate cancers.—“Now is the time to aggressively pursue the protective benefits of coffee against Alzheimer’s disease,” Dr. Arendash said. “Hopefully, the coffee industry will soon become an active partner with Alzheimer’s researchers to find the protective ingredient in coffee and concentrate it in dietary sources.”–New Alzheimer’s diagnostic guidelines, now encompassing the full continuum of the disease from no overt symptoms to mild impairment to clear cognitive decline, could double the number of Americans with some form of the disease to more than 10 million. With the baby-boomer generation entering older age, these numbers will climb even more unless an effective preventive measure is identified.—“Because Alzheimer’s starts in the brain several decades before it is diagnosed, any protective therapy would obviously need to be taken for decades,” Dr. Cao said. “We believe moderate daily consumption of caffeinated coffee is the best current option for long-term protection against Alzheimer’s memory loss. Coffee is inexpensive, readily available, easily gets into the brain, appears to directly attack the disease process, and has few side-effects for most of us.”—According to the researchers, no other Alzheimer’s therapy being developed comes close to meeting all these criteria.—“Aside from coffee, two other lifestyle choices — physical and cognitive activity — appear to reduce the risk of dementia. Combining regular physical and mental exercise with moderate coffe
    e consumption would seem to be an excellent multi-faceted approach to reducing risk or delaying Alzheimer’s,” Dr. Arendash said. “With pharmaceutical companies spending millions of dollars trying to develop drugs against Alzheimer’s disease, there may very well be an effective preventive right under our noses every morning — caffeinated coffee.”–This USF study was funded by the NIH-designated Florida Alzheimer’s Disease Research Center and the State of Florida.–Story Source-The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of South Florida (USF Health), via EurekAlert!, a service of AAAS.—-Journal Reference-Chuanhai Cao, Li Wang, Xiaoyang Lin, Malgorzata Mamcarz, Chi Zhang, Ge Bai, Jasson Nong, Sam Sussman and Gary Arendash. Caffeine Synergizes with Another Coffee Component to Increase Plasma GCSF: Linkage to Cognitive Benefits in Alzheimer’s Mice. Journal of Alzheimer’s Disease, 25(2), June 28, 2011
    Recipe—take coffee beans ( chose your favourite ) and add ¼ cup to a blender—then add a clear base alcohol to the blender as well ½-3/8 cup—blend for 10 minutes or til heated—then strain and add to a glass container—utilize ¼ tsp to ½ ( you can increase til you see where you are tolerant –this will be a starting point ) and do this several times a day—you will get the antioxidant benefit- the stimulation—the increased oxygen uptake and the protective properties toward brain diseases—————————————————– You can as well as an alternative to increase the effect-after you strain the mix put the strained mix in a pot and simmer down to about half to remove the water out and to further potent the coffee effects—and use ¼ tsp—if to strong then add to coffee –
    Recipe 2 –add creatine to your coffee to further protect the brain from head traumas as well as other brain dysfuntions—use 3-5grams ( 1 gram = 1000mgs)
    Recipe 3 add ½ cup of honey-1/4 cup of rosemary extract and add ¼ cup of coffee bean ( even a powdered expresso ) and blend at high speed for 10 minutes—add to a glass jar and again use ¼-1/2 tsp increments daily or add to coffee
    Make sure when consuming coffee it is Black—add maple syrup—unpasteurized honey or xylitol or stevia only to sweeten it if need to
    BHT –The Healing effects
    BHT is an antioxidant and common food preservative, approved by the FDA for food, oils and fats. Over 25 years ago, a paper was published in the journal Science showing that BHT could inactivate herpes simplex and other lipid coated viruses in vitro (In lab dishes).(1) This was followed by another paper published in Science showing that BHT could prevent chickens from dying of Newcastle disease.(2) The herpes virus and the virus that causes Newcastles disease have a lipid envelope. That is, the nucleic acid core of these viruses is coated with a fatty membrane. Viruses of this type require an intact lipid membrane in order to penetrate cell walls and infect living cells.
    BHT appears to work against such viruses by disrupting their lipid membranes making them vulnerable to the immune system and imparing their ability to penetrate human cells. BHT also removes binding proteins that the virus uses to penetrate cell membranes. In addition, BHT acts as an antioxidant neutralizing free radicals that damage cell membranes and cause inflammation. It is believed that the destructive action of many pathogenic viruses involves the destructive action of free radicals on cellular membranes. More recent studies have confirmed the anti-viral activity of BHT against many different human and animal viruses including CMV (cytomegalovirus), (3) pseudorabies (4), genital herpes (5), HIV (6) and some strains of influenza.(7) — A few of the viruses that have a lipid envelope and may be affected by BHT include herpes simplex I, herpes simplex II, herpes zoster, ckytomegalovirus, west nile virus, HIV virus, influenza virus, hepatitis B and C viruses, avian flu influenza virus and the SARS virus. Remember that BHT has not been clinically tested and approved to treat these infections.– Based on these early scientific results, some individuals afflicted with herpes virus infections began experimenting on themselves with BHT. They used dosages in the 250 to 3000 mg. per day range with the result that they experienced a reduction in herpes outbreaks. For some, their eruptions remained suppressed for as long as they continued to take BHT daily. For others, they were able to eventually discontinue taking BHT with no recurrences. BHT is discussed in Mann and Fowke’s book “Wipe Out Herpes with BHT” and Pearson and Shaw’s book “Life Extension”.(8)(9) At issue is that none of the controlled studies on the antiviral properties of BHT have been performed on humans. Rather, most of the experiments have been conducted in the laboratory or on animals. In addition, BHT is a common, inexpensive substance that is unpatentable. No pharmaceutical company will invest money in researching and certifying its value as a medication. Furthermore, it may be difficult to perform human trials because the Food and Drug Administration (FDA) has approved BHT for use only as a food preservative, not as a medicine.— Therefore, it is not approved for the treatment of herpes infections or any other disease. While doctors have the authority to prescribe BHT, they could face peer pressure and malpractice insurance issues for using unapproved treatments. You are, therefore, unlikely to get a doctor to recommend or prescribe BHT. If you decide to make an independent decision to take BHT, at least tell your doctor what you are doing so that he can give you advice regarding your diagnosis, your other treatment options, potential consequences, possible drug interactions, etc.
    The lack of approval hasn’t stopped some people from using BHT on their own to treat herpes or other viral conditions. While there is no accounting of how many people have used BHT to treat herpes and other viral infections, the estimates run from tens of thousands to hundreds of thousands.
    BHT Safety Concerns and Side Effects
    Studies performed on rats demonstrated liver and kidney damage at doses of 0.5 to 1.0 grams per kilogram.(10) This is the equivalent of a 160 pound adult taking 73 grams per day. Compare this to a typical suppressing dose of 0.25 to 0.50 grams per day and a typical dosage for an acute outbreak of 1.0 to 2.0 grams per day. No evidence was noted for BHT causing cancer and conflicting results were obtained regarding effects on the immune system, tumor formation and other effects. Again all of these tests were done on rats and usually using high doses far in excess of therapeutic dosages.– BHT is metabolized by the liver and some of the rat experiments showed a suppression of liver enzymes and enlargement of the liver. This implies a degree of liver toxicity if the dose is high enough. At what dose a human might experience some degree of liver toxicity is unclear. Liver toxicity is a common side effect of a great many medications including some common over the counter pain relievers. If you are taking BHT or choose to take BHT, consider asking your doctor to do a blood test to measure your liver enzymes. [U1]— A large number of individuals have taken BHT in therapeutic doses for extended periods of time with no reported adverse effects. (8)(9) A case was reported in The New England Journal of Medicine of a patient who took 4 grams of BHT as a single dose on an empty stomach and experienced severe gastric pain, nausea, vomiting and dehydration.(11) To be fair, a number of substances including aspirin, vitamin and mineral supplements some foods and many common medications can produce similar effects when taken on an empty stomach.— Additional anecdotal reports indicated that BHT may cause hives in a few individuals who are sensitive to BHT[U2]. BHT was also observed to temporarily cause a decrease in blood clotting when individuals first begin taking it in substantial doses. One individual reported dizziness and disorientation when taking 3 grams per day. His symptoms disappeared when he dropped his dose down to 250 mg. per day. (8)(9)– There are a few physicians who regularly prescribe BHT for herpes treatment and outbreak prevention and consider it safe. There have been no formal clinical trials on humans to definitively determine the safety status of BHT.
    BHT Dosage
    Based on anecdotal information, it appears that a dosage of 250 mg. to 1000 mg. per day may be effective for many people. Dr. Ward Dean, M.D. recommends a dosage of 250 to 500 mg. per day as an anti-oxidant and 2000 mg. per day in divided doses for acute herpes outbreaks.(12) Anecdotal evidence also suggests that therapy at this dosage may be insufficient to suppress herpes outbreaks in some individuals. It is hypothesized that combining BHT with other measures, either alternative or orthodox, may be more effective than using BHT alone.
    More info
    How Cavity-Causing Microbes Invade Heart
    S. mutans invading a human coronary artery endothelial cell. —ScienceDaily (June 28, 2011) — Scientists have discovered the tool that bacteria normally found in our mouths use to invade heart tissue, causing a dangerous and sometimes lethal infection of the heart known as endocarditis. The work raises the possibility of creating a screening tool — perhaps a swab of the cheek, or a spit test — to gauge a dental patient’s vulnerability to the condition.—The identification of the protein that allows Streptococcus mutans to gain a foothold in heart tissue is reported in the June issue of Infection and Immunity by microbiologists at the University of Rochester Medical Center.—S. mutans is a bacterium best known for causing cavities. The bacteria reside in dental plaque — an architecturally sophisticated goo composed of an elaborate molecular matrix created by S. mutans that allows the bacteria to inhabit and thrive in our oral cavity. There, they churn out acid that erodes our teeth.-[U3] Normally, S. mutans confines its mischief to the mouth, but sometimes, particularly after a dental procedure or even after a vigorous bout of flossing, the bacteria enter the bloodstream. There, the immune system usually destroys them, but occasionally — within just a few seconds — they travel to the heart and colonize its tissue, especially heart valves. The bacteria can cause endocarditis — inflammation of heart valves — which can be deadly. Infection by S. mutans is a leading cause of the condition.- “When I first learned that S. mutans sometimes can live in the heart, I asked myself: Why in the world are these bacteria, which normally live in the mouth, in the heart? I was intrigued. And I began investigating how they get there and survive there,” said Jacqueline Abranches, Ph.D., a microbiologist and the corresponding author of the study.–Abranches and her team at the University’s Center for Oral Biology discovered that a collagen-binding protein known as CNM gives S. mutans its ability to invade heart tissue. In laboratory experiments, scientists found that strains with CNM are able to invade heart cells, and strains without CNM are not.–When the team knocked out the gene for CNM in strains where it’s normally present, the bacteria were unable to invade heart tissue. Without CNM, the bacteria simply couldn’t gain a foothold; their ability to adhere was about one-tenth of what it was with CNM.[U4]– The team also studied the response of wax worms to the various strains of S. mutans. They found that strains without CNM were rarely lethal to the worms, while strains with the protein were lethal 90 percent of the time. Then, when Abranches’ team knocked out CNM in those strains, they were no longer lethal — those worms thrived.–The work may someday enable doctors to prevent S. mutans from invading heart tissue. Even sooner, though, since some strains of S. mutans have CNM and others do not, the research may enable doctors to gauge a patient’s vulnerability to a heart infection caused by the bacteria.—Abranches has identified five specific strains of S. mutans that carry the CNM protein, out of more than three dozen strains examined. CNM is not found in the most common type of S. mutans found in people, type C, but is present in rarer types of S. mutans, including types E and F.—“It may be that CNM can serve as a biomarker of the most virulent strains of S. mutans,” said Abranches, a research assistant professor in the Department of Microbiology and Immunology. “When patients with cardiac problems go to the dentist, perhaps those patients will be screened to see if they carry the protein. If they do, the dentist might treat them more aggressively with preventive antibiotics,[U5] for example.”–Until more research is done and a screening or preventive tool is in place, Abranches says the usual advice for good oral health still stands for everyone.–“No matter what types of bacteria a person has in his or her mouth, they should do the same things to maintain good oral health. They should brush and floss their teeth regularly — the smaller the number of S. mutans in your mouth, the healthier you’ll be. Use a fluoride rinse[U6] before you go to bed at night. And eat a healthy diet, keeping sugar to a minimum,” added Abranches.–Abranches presented the work at a recent conference on the “oral microbiome” hosted by the University’s Center for Oral Biology. The center is part of the Medical Center’s Eastman Institute for Oral Health, a world leader in research and post-doctoral education in general and pediatric dentistry, orthodontics, periodontics, prosthodontics, and oral surgery.–Additional authors of the study include laboratory technician James Miller; former technician Alaina Martinez; Patricia Simpson-Haidaris, Ph.D., associate professor of Medicine; Robert Burne, Ph.D., of the University of Florida; and Abranches’ husband, Jose Lemos, Ph.D., of the Center for Oral Biology, who is also assistant professor in the Department of Microbiology and Immunology. The work was funded by the American Heart Association.–Story Source-The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Rochester Medical Center.-Journal Reference-J. Abranches, J. H. Miller, A. R. Martinez, P. J. Simpson-Haidaris, R. A. Burne, J. A. Lemos. The Collagen-Binding Protein Cnm Is Required for Streptococcus mutans Adherence to and Intracellular Invasion of Human Coronary Artery Endothelial Cells. Infection and Immunity, 2011; 79 (6): 2277 DOI: 10.1128/IAI.00767-10
    Special Note—those who have artificial teeth or plates or anything inserted in the mouth will have to keep a constant vigilance on the bacterial growth and will need to maintain those plates to be optimally clean—if this kind of procedure has been done from metals to plastics or polymers then it is imperative you use antibacterials- antifungals and anti virals where these things can cling to those artificial or synthetic teeth– without the harsh brushing—utilizing even a good oil pulling with an essential oil mix or an alcohol solution with different essential oils or make extracts and gargle and utilize the swishing and the pushing and pulling effect with these solutions
    Turning Vicks into Mutli Remedy
    Go to the dollar store and get a vicks generic ( or vicks)—it will have in it camphor-menthol and eucalyptus—what we are going to do is enhance this—we are going to add Iodine to it say 1 tsp we are going to add turpentine to it 1 tsp and mix well thuja 1 tsp ( you can as well use other things like pepper ( red) or even other essential oils and ratio it out to your own spec’s—
    Once mixed add to any area where there is an over growth or if you have a infection in an area or if you have a toe fungus or itchy feet—if you have respiratory issues going on and cannot breathe or are backed up as a result of a mucous overload—if you have aches and pains of arthritic issues whether they be hands or joints—this will kill of fungus—yeast—viral—bacterial will act as a antiseptic—will act as a respiratory support—circulation support—analgesic—high levels of antioxidants as well—can be used anywhere except the genitals and the backside due to the heat and penetration it can make sensitive areas respond negatively—avoid eyes as well—Apply to one area and massage in for about 2-3 minutes—if you feel anything coming out rinse hands and re do till full absorbed into the skin
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    [U1]Or Utilize NAC or Methionine or MSM or Alpha Lipoic acid with this regimen—this will insure the protection of the liver and as well utilize either Sage- Milk thistle-or artichoke as well
    [U2]This could as a result of removing the free radicals releasing a histamine response as well
    [U3]BAKING SODA anyone GSE—Peroxide—Thyme-Peppermint-MYRHH—seems to me we may have the perfect solution already—and if it can thrive then maybe we beed to see where this protein is coming from and eliminate the food source or food waste that we maybe consuming
    [U4]Enzymes anyone—Serrepeptase—Protease—Bromelain—Papain–
    [U5]Again the idiocy of this treatment—fix one thing anc cause 20 others to go bad—if you were using enzymes and and antibacterials from herbs or supplements you could do the same thing and resisited the temptation of consuming genetic modified proteins that may carry this
    [U6]REJECT THIS—UNECESSARY—even using GSE—Baking SODA—Myrrh-Peppermint Essrntial oil—thyme essential oil—anything that will neutralize and balnce the chemistry in the ooral cavity even the use of peroxide–
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    Show of the Week July 8 2011
    EU herbal directive will close health food stores, say owners
    ANH: Herbal Medicinal Products Directive is “a protectionist tool
    Drug Expiration Date
    Pine Bark Meal
    Treats and Foods with a Twist
    EU herbal directive will close health food stores, say owners
    Health food store owners are warning they will be forced to close down after April 30 this year, when the European Union Traditional Herbal Medicinal Products Directive (THMPD) kicks in.
    Companies have had a seven year-grace period since the THMPD entered EU law books in 2004, but EU-wide registrations under the regulation have been chronically low, meaning unless thousands of products register in the coming months, they will be stripped from health store and other retail shelves. —Selwyn Soe of the London-based The Herbal Factory told the BBC: “Unfortunately it looks as if we will have to close down because of this legislation.” —“The problem for us is that although we would have to pay many thousands of pounds for a licence to keep making each product, unlike a drug company we would not have a licence to make that product exclusively. It just will not be worth paying out the money.” –The regulation requires all herbal products making health and medicinal claims to be registered. As of December 31, 2010, there had been 187 registrations for individual products in the UK. Eighty four products had been approved and none rejected. —-The 100 per cent success rate has been attracting the interest of food supplement manufacturers and herbal ingredient suppliers who have struggled to have their science accepted under the 2006 nutrition and health claims regulation (NHCR). —But herbal sector observers and associations have been surprised by the lack of THMPD registration applications – with the UK leading the way, followed by Germany, but many member states recording no applications at all. The relative high cost of registrations is deemed as partly to blame for the situation. — The fact that there is a clear discrepancy between the way science is treated under the THMPD and the NHCR has caused some confusion, and was partially responsible for the European Commission recently removing botanicals from the NHCR process to reconsider how science in the sector should be treated. –That issue is unlikely to be revisited until the end of 2011.
    ANH: Herbal Medicinal Products Directive is “a protectionist tool”
    The Alliance for Natural Health International has slammed the European Commission’s Traditional Herbal Medicinal Products Directive as “a protectionist tool.”
    In an open letter to European commissioner John Dalli, Robert Verkerk, the alliance’s founder and scientific director wrote: “It seems that the criticism you now face in some quarters is down to the creation by the EU of what is effectively a protectionist tool; one which favours certain products of the European phytopharmaceutical system and discriminates against those of non-European traditional systems of medicine.” –Verkerk’s letter follows a forum in the European Parliament on 21 June to consider the challenges posed by the Traditional Herbal Medicinal Products Directive (THMPD Directive 2004/24/EC) to traditional systems of medicine; particularly those of non-European origin.
    Herbal practitioner
    The new legislation requires that traditional herbal medicinal products, many of which have been used in Europe for decades, must be licensed or prescribed by a registered herbal practitioner in order to comply with a directive passed in 2004 and implement on May 1 2004. –In the UK, for example, over-the-counter herbal medicine products require either a Traditional Herbal Medicines Registration (THR) or a full marketing authorisation. To be eligible for a licence, products must have been on the market for 30 years, including 15 within the EU. —So far, only about 100 herbal products have been registered under the THR scheme, which is run by the Medicines and Healthcare Products Regulatory Agency (MHRA). This could mean that thousands of products may eventually be banned. —But in a letter to Giles Chichester MEP on 13 April 2011, Dalli said that there were no additional barriers to the registration of Ayurvedic and traditional Chinese medicine (TCM) compared with products from other European traditions. —Verkerk responded by writing: “By contrast not a single product authentic to the Ayurvedic, Unani, TCM, Tibetan, Thai, southern African or Amazonian – or, indeed any other non European – system has yet been registered.” –The open letter goes on to list four barriers allegedly preventing the uptake of registrations among the non-European traditions. Those are claimed to be: Eligibility limitations, technical limitations, excessive cost, and lack of incentive. –The eligibility barrier refers to traditional use requirement specifying at least 15 years useage within the EU. “This locks out many products which that may have been used for decades or even centuries, or even millennia outside the EU,” wrote Verkerk.
    Technical limitations –Technical limitations refer to the pharmaceutical and stability standards set out in the European Medicines Agency (EMA) guidelines. These are more straightforward for single-herb products or limited combinations than for most authentic traditional herbal medicinal products which are often whole herb or aqueous extractions. —Registration fees varying from €2,000 to €50,000 per product are “…unquestionably out of reach of the small-to-medium sized enterprises (SME) supplying products associated with non-European traditional systems,” wrote Verkerk. –Finally, a lack of financial incentive to register non-European medicines is said to be a powerful disincentive to take up registrations. —Verkerk ends his open letter with a plea for Dalli to comment on his concerns and for the Commission to consider the feasibility of a new regulatory framework more appropriate for holistic systems of medicine. No one from the Commission was available to respond to Verkerk’s criticisms. But an EC spokeswoman promised a response by the end of next month.