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    VACCINE INGREDIENTS …AND THEIR CHEMICAL PROFILES
    Compiled By Arthur M. Evangelista, a former FDA Investigator
     
    Posted: 28 May 2004
     
    VACCINE INGREDIENTS
    Source: 1997 Physicians’ Desk Reference
    Toll Free Numbers can be called to obtain product inserts.
    This is a representative, not a comprehensive, list of the various types of vaccines.
    Acel-Immune
    DTaP
    Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed
    Lederle Laboratories
    1-800-934-5556
    produced using formaldehyde, thimerosal, aluminum hydroxide, aluminum phosphate, polysorbate 80, gelatin (animal parts/bovine)
    Act HIB
    Haemophilus Influenzae Type B (Hib) Tetanus Toxoid Conjugate
    Connaught Laboratories
    1-800-822-2463
    produced using ammonium sulfate, formalin, sucrose, thimerosal
    medium: semi-synthetic
    Attenuvax
    Measles Virus Vaccine Live
    Merck & Co, Inc.
    1-800-672-6372
    produced using neomycin, sorbitol, hydrolized gelatin
    medium: chick embryo
    DPT
    Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed
    SmithKline Beecham Pharmaceuticals
    1-800-366-8900 ext. 5231
    produced using aluminum phosphate, formaldehyde, ammonium sulfate, washed sheep red blood cells, glycerol, sodium chloride, thimerosal
    medium: porcine (pig) pancreatic hydrolysate of casein
    Energix-B
    Hepatitis B
    SmithKline Beecham Pharmaceuticals
    1-800-633-8900 ext. 5231
    produced using aluminum hydroxide, thimerosal
    medium: yeast (possibly 5% residual)
    Havrix
    Hepatitis A
    SmithKline Beecham Pharmaceuticals
    1-800-633-8900 ext. 5231
    produced using formalin, aluminum hydroxide, phenoxyethanol (antifreeze), polysorbate 20, residual MRC5 proteins (from medium)
    medium: human diploid cells (originating from human aborted fetal tissue)
    Biavax
    Rubella and Mumps Virus Vaccine Live
    Merck & Co, Inc.
    1-800-672-6372
    produced using neomycin, sorbitol, hydrolized gelatin
    medium: human diploid cells (originating from human aborted fetal tissue)
    HibTiter
    Haemophilus Influenzae Type B (Hib)
    Lederle Laboratories
    1-800-934-5556
    produced using polyribosylribitol, ammonium sulfate, thimerosal
    medium: chemically defined, yeast based
    Fluvirin
    Influenza Virus Vaccine
    Medeva Pharmaceuticals
    1-888-MEDEVA
    (716)274-5300
    produced using embryonic fluid (chicken egg), neomycin, polymyxin, thimerosal, betapropiolactone
    medium: embryonic fluid (chicken egg)
    FluShield
    Influenza Virus Vaccine, Trivalent, Types A&B
    Wyeth-Ayerst
    1-800-934-5556
    produced using gentamicin sulfate, formaldehyde, polysorbate 80, tri(n)butylphosphate, thimerosal
    medium: chick embryos
    IPOL
    Inactivated Polio Vaccine
    Connaught Laboratories
    1-800-822-2463
    produced using 3 types of polio virus, formaldehyde, phenoxyethanol (antifreeze), neomycin, streptomycin, polymyxin B
    medium: VERO cells, a continuous line of monkey kidney cells
    MMR
    Measles Mumps Rubella Live Virus Vaccine
    Merck & Co., Inc.
    1-800-672-6372 produced using sorbitol, neomycin, hydrolyzed gelatin
    mediums: M&M – chick embryo
    Rubella – human diploid cells (originating from human aborted fetal tissue)
    M-R-Vax
    Measles and Rubella Virus Vaccine Live
    Merck & Co., Inc.
    1-800-672-6372
    produced using neomycin, sorbitol, hydrolyzed gelatin
    mediums: M – chick embryo
    R – human diploid cells (originating from human aborted fetal tissue)
    Menomune
    Meningococcal Polysaccharide Vaccine
    Connaught Laboratories
    1-800-822-2463
    produced using thimerosal, lactose
    medium: freeze dried polysaccharride antigens from Neisseria Meningitidis
    Meruvax II
    Rubella Virus Vaccine Live
    Merck & Co., Inc.
    1-800-672-6372
    produced using neomycin, sorbitol, hydrolyzed gelatin
    medium: human diploid cells (originating from human aborted fetal tissue)
    Mumpsvax
    Mumps Virus Vaccine Live
    Merck & Co., Inc.
    1-800-672-6372
    produced using neomycin, sorbitol, hydrolyzed gelatin
    medium: human diploid cells (originating from human aborted fetal tissue)
    Orimune
    Poliovirus Vaccine Live Oral Trivalent
    Lederle Laboratories
    1-800-934-5556
    produced using 3 types of attenuated polioviruses, streptomycin, neomycin, calf serum, sorbitol
    medium: monkey kidney cell culture
    Pneumovax
    Pneumococcal Vaccine Polyvalent
    Merck & Co., Inc.
    1-800-672-6372
    produced using phenol and capsular polysaccharides from the 23 most prevalent pneumococcal types
    Imovax
    Rabies Vaccine Adsorbed
    Connaught Laboratories
    1-800-822-2463
    produced using human albumin, neomycin sulfate, phenol red indicator
    medium: human diploid cells (originating from human aborted fetal tissue)
    Rabies Vaccine Adsorbed
    SmithKline Beecham Pharmaceuticals
    1-800-366-8900 ext. 5231
    produced using betapropiolactone, aluminum phosphate, sodium ethylmercurithiosalicylate (thimerosal), phenol red
    medium: fetal rhesus monkey lung cells
    Recombivax
    Hepatitis B Vaccine Recombinant
    Merck & Co., Inc.
    1-800-672-6372
    produced using thimerosal, aluminum hydroxide
    medium: yeast (residual < 1% yeast protein)
    RotaShield
    Rotavirus Vaccine, Live, Oral, Tetravalent
    Wyeth-Ayerst Laboratories
    1-800-934-5556
    produced using 1 rhesus monkey rotavirus, 3 rhesus-human reassortant viruses, sucrose, monosodium glutamate (MSG), potassium monophosphate, potassium diphosphate, fetal bovine serum, neomycin sulfate, amphotericin B
    medium: fetal rhesus diploid cell line
    Varivax
    Varicella Virus Vaccine Live
    Merck & Co., Inc.
    1-800-672-6372
    produced using sucrose, phosphate, glutamate, processed gelatin
    medium: human diploid cells (originating from human aborted fetal tissue)
     
    Chemical Profiles and Definitions
    visit http://www.scorecard.org/ to investigate chemical profiles
    Sources: EDF (Environmental Defense Fund) & MME (Mosby’s Medical Encyclopedia)
    Ammonium Sulfate: EDF Suspected – gastrointestinal or liver toxicant, neurotoxicant, respiratory toxicant
    Amphotericin B: MME definintion – “a drug used to treat fungus infections. Known allergy to this drug prohibits use. Side effects include blood clots, blood defects, kidney problems, nausea and fever. When used on the skin, allergic reactions can occur.”
    Aluminum: EDF Suspected – cardiovascular, or blood toxicant, neurotoxicant, respiratory toxicant.
    More hazardous than most chemicals in 2 out of 6 ranking systems.
    On at least 2 federal regulatory lists.
    Beta-Propiolactone: EDF Recognized – carcinogen
    EDF Suspected – gastrointestinal or liver toxicant; respiratory toxicant; skin or sense organ toxicant.
    More hazardous than most chemicals in 3 out of 3 ranking systems.
    On at least 5 federal regulatory lists ranked as one of the most hazardous compounds (worst 10%) to humans.
    Formaldehyde: EDF Recognized – carcinogen
    Suspected – gastrointestinal or liver toxicant; immunotoxicant, neurotoxicant, reproductive toxicant; respiratory toxicant; skin or sense organ toxicant.
    More hazardous than most chemicals in 5 out of 12 ranking systems.
    On at least 8 federal regulatory lists ranked as one of the most hazardous compounds (worst 10%) to ecosystems and human health.
    Gentamicin Sulfate: an antibiotic
    Hydrolyzed Gelatin: obtained from selected pieces of calf and cattle skins, de-mineralized cattle bones (ossein) and porkskin.
    Neomycin: an antibiotic
    Phenol : EDF Suspected – cardiovascular or blood toxicant aka Carbolic Acid – developmental toxicant, gastrointestinal or liver toxicant kidney toxicant, neurotoxicant respiratory toxicant, skin or sense organ toxicant.
    More hazardous than most chemicals in 3 out of 10 ranking systems.
    On at least 8 federal regulatory lists.
    Phenoxyethanol: EDF Suspected – developmental toxicant, reproductive toxicant (aka: Antifreeze).
    Less hazardous than most chemicals in 3 ranking systems.
    Polyribosylribitol: a component of the Hib bacterium
    Polymyxin: an antibiotic
    Polysorbate: EDF Suspected – skin or sense organ toxicant
    Sorbitol: EDF Suspected – gastrointestinal or liver toxicant.
    Less hazardous than most chemicals in 1 ranking system.
    Streptomycin: an antibiotic
    Sucrose: refined sugar
    Thimerosal: EDF Recognized – developmental toxicant. Suspected – skin or sense organ toxicant.
    Tri(n)butylphosphate: EDF Suspected – kidney toxicant neurotoxicant.
    More hazardous than most chemicals in 2 out of 3 ranking systems.
    On at least 1 federal regulatory list.
    “We have a duty to look after each other. If we lose control of our government, then we lose our ability to dispense justice and human kindness. Our first priority today, then, is to defeat utterly those forces of greed and corruption that have come between us and our self-governance